Table A4.

Median overall survival of combinations of HIF signaling geneset and BMP signaling genesets.

Genesets	Semenza Hif1 Targets **
	Low	High
bmp receptor signaling
Low	20.3 (n = 19)	9 (n = 13)
High	22.65 (n = 16)	16.55 (n = 22)
regulation of bmp signaling pathway
Low	24 (n = 17)	8.1 (n = 12)
High	18.1 (n = 18)	14.1 (n = 23)
response to bmp
Low	20 (n = 16)	8.7 (n = 13)
High	23.3 (n = 19)	14.1 (n = 22)
signaling by bmp
Low	18 (n = 17)	11.25 (n = 18)
High	24.45 (n = 18)	11 (n = 17)
reactome signaling by bmp
Low	18 (n = 19)	10.2 (n = 16)
High	24.45 (n = 16)	11.6 (n = 19)

** p-value < 0.01.