. 2020 Nov 23;8:e10419. doi: 10.7717/peerj.10419

Table 1. A total of 263 DEGs were identified from the three microarray datasets, which consisted of 167 upregulated genes and 96 downregulated genes present in pancreatic ductal adenocarcinoma (PDAC) tissues in comparison with non-tumor tissues.

DEGs	Gene names
Upregulated	XDH, RTKN2, PTPRR, ADAM12, STYK1, TPX2, PADI1, HEPH, CEACAM6, ITGA3, COL1A1, ANLN, FNDC1, PCDH7, SLC6A6, TRIM29, PXDN, EDNRA, LTBP1, MFAP5, PLA2R1, FN1, KRT17, PGM2L1, IFI27, ASAP2, LAMB3, TNFAIP6, HOXB5, OAS1, NTM, COL5A2, OSBPL3, TMPRSS4, ANTXR1, SDR16C5, OLR1, NT5E, CTSK, SULF2, MXRA5, APOL1, CDH11, AREG, MALL, S100A16, BGN, LAMA3, COL8A1, IGFBP5, MMP12, ADAMTS6, SLC2A1, CD109, ECT2, KIF23, MMP11, CDH3, LMO7, CCL18, ATP2C2, POSTN, MMP14, ADAM28, SRPX2, CEACAM5, TMC5, OAS2, MUC17, GABRP, COMP, SYTL2, GPX8, RUNX2, DLGAP5, KRT19, VCAN, MKI67, SULF1, LAMC2, GCNT3, NMU, MUC13, CEACAM1, ETV1, COL12A1, AGR2, ST6GALNAC1, SLC44A4, PLAU, S100P, SERPINB5, FOXQ1, TGM2, ITGB4, DCBLD2, TRIM31, RAI14, NRP2, SGIP1, CST1, ARNTL2, LEF1, MYOF, ANO1, S100A14, DDX60, KYNU, CAPG, CCL20, MATN3, NPR3, GPRC5A, NOX4, IL1RAP, ACSL5, HPGD, GREM1, SCEL, FBN1, IGFL2, SLC6A14, KRT6A, DHRS9, ANGPT2, MST1R, COL3A1, TMEM45B, EDIL3, ASPM, FAP, INPP4B, LOXL2, NQO1, CYP2C18, IFI44L, HK2, EFNB2, AEBP1, SLC16A3, CORIN, THBS2, BCAS1, DSG3, DKK1, RHBDL2, COL17A1, TSPAN1, FERMT1, CXCL5, COL6A3, COL10A1, ACTA2, PLAC8, AHNAK2, MLPH, FBXO32, TGFBI, KCNN4, CLDN18, FGD6, MTMR11, FXYD3, MBOAT2, SEMA3C, DPYSL3, CENPF
Downregulated	EPB41L4B, GSTA2, KIAA1324, CELA3A, ACADL, CEL, SLC39A5, LONRF2, SLC3A1, NRG4, MT1G, PROX1, G6PC2, C5, EGF, FAM3B, AQP8, CLPS, SLC17A4, CPB1, GP2, PDK4, RBPJL, PDIA2, PM20D1, CTRC, IAPP, PLA2G1B, ERP27, CELA2B, GRPR, REG1A, KIF1A, GUCA1C, CTRL, SYCN, CHRM3, TMED6, ALB, KCNJ16, REG3A, SLC4A4, AOX1, SERPINA5, CELA2A, SPINK1, FAM129A, FAM150B, SLC16A12, F11, CPA2, SV2B, BNIP3, C2CD4B, SLC1A2, REG1B, SCGN, PAK3, PRSS3, GRB14, REG3G, DCDC2, F8, GPHA2, EPHX2, PNLIPRP2, SLC7A2, CPA1, PRKAR2B, ONECUT1, BACE1, NUCB2, HOMER2, CXCL12, SLC43A1, GNMT, NR5A2, ALDH1A1, IL22RA1, BEX1, ANPEP, CFTR, FLRT2, LMO3, FGL1, NRCAM, FABP4, PNLIPRP1, KLK1, SERPINI2, GATM, DPP10, C6, SLC16A10, PRSS1, PAH

DEGs

Gene names

Upregulated

XDH, RTKN2, PTPRR, ADAM12, STYK1, TPX2, PADI1, HEPH, CEACAM6, ITGA3, COL1A1, ANLN, FNDC1, PCDH7, SLC6A6, TRIM29, PXDN, EDNRA, LTBP1, MFAP5, PLA2R1, FN1, KRT17, PGM2L1, IFI27, ASAP2, LAMB3, TNFAIP6, HOXB5, OAS1, NTM, COL5A2, OSBPL3, TMPRSS4, ANTXR1, SDR16C5, OLR1, NT5E, CTSK, SULF2, MXRA5, APOL1, CDH11, AREG, MALL, S100A16, BGN, LAMA3, COL8A1, IGFBP5, MMP12, ADAMTS6, SLC2A1, CD109, ECT2, KIF23, MMP11, CDH3, LMO7, CCL18, ATP2C2, POSTN, MMP14, ADAM28, SRPX2, CEACAM5, TMC5, OAS2, MUC17, GABRP, COMP, SYTL2, GPX8, RUNX2, DLGAP5, KRT19, VCAN, MKI67, SULF1, LAMC2, GCNT3, NMU, MUC13, CEACAM1, ETV1, COL12A1, AGR2, ST6GALNAC1, SLC44A4, PLAU, S100P, SERPINB5, FOXQ1, TGM2, ITGB4, DCBLD2, TRIM31, RAI14, NRP2, SGIP1, CST1, ARNTL2, LEF1, MYOF, ANO1, S100A14, DDX60, KYNU, CAPG, CCL20, MATN3, NPR3, GPRC5A, NOX4, IL1RAP, ACSL5, HPGD, GREM1, SCEL, FBN1, IGFL2, SLC6A14, KRT6A, DHRS9, ANGPT2, MST1R, COL3A1, TMEM45B, EDIL3, ASPM, FAP, INPP4B, LOXL2, NQO1, CYP2C18, IFI44L, HK2, EFNB2, AEBP1, SLC16A3, CORIN, THBS2, BCAS1, DSG3, DKK1, RHBDL2, COL17A1, TSPAN1, FERMT1, CXCL5, COL6A3, COL10A1, ACTA2, PLAC8, AHNAK2, MLPH, FBXO32, TGFBI, KCNN4, CLDN18, FGD6, MTMR11, FXYD3, MBOAT2, SEMA3C, DPYSL3, CENPF

Downregulated

EPB41L4B, GSTA2, KIAA1324, CELA3A, ACADL, CEL, SLC39A5, LONRF2, SLC3A1, NRG4, MT1G, PROX1, G6PC2, C5, EGF, FAM3B, AQP8, CLPS, SLC17A4, CPB1, GP2, PDK4, RBPJL, PDIA2, PM20D1, CTRC, IAPP, PLA2G1B, ERP27, CELA2B, GRPR, REG1A, KIF1A, GUCA1C, CTRL, SYCN, CHRM3, TMED6, ALB, KCNJ16, REG3A, SLC4A4, AOX1, SERPINA5, CELA2A, SPINK1, FAM129A, FAM150B, SLC16A12, F11, CPA2, SV2B, BNIP3, C2CD4B, SLC1A2, REG1B, SCGN, PAK3, PRSS3, GRB14, REG3G, DCDC2, F8, GPHA2, EPHX2, PNLIPRP2, SLC7A2, CPA1, PRKAR2B, ONECUT1, BACE1, NUCB2, HOMER2, CXCL12, SLC43A1, GNMT, NR5A2, ALDH1A1, IL22RA1, BEX1, ANPEP, CFTR, FLRT2, LMO3, FGL1, NRCAM, FABP4, PNLIPRP1, KLK1, SERPINI2, GATM, DPP10, C6, SLC16A10, PRSS1, PAH