Table 5.
Multivariable analysis of clinical and imaging features and OS
| Variable | HR | P |
|---|---|---|
| Age | 0.0187 | |
| <3 | 0.76 | |
| 3–10 | 1.00 | |
| 10+ | 0.66 | |
| Symptom duration | 0.1164 | |
| <6 weeks | 1.00 | |
| 6–12 weeks | 0.78 | |
| 12–24 weeks | 0.76 | |
| >24 weeks | 0.60 | |
| Chemo | 0.45 | <0.0001 |
| Extension beyond Pons or BP | 1.10 | 0.9247 |
| AP Tumor dimension | 0.99 | 0.3246 |
| Trans Tumor dimension | 1.00 | 0.8672 |
| CC Tumor dimension | 1.01 | 0.1996 |
| AP Tumor / AP pons ratio | 2.26 | 0.0631 |
| Beyond Pons | 1.33 | 0.7807 |
| Enhancement (any) | 1.21 | 0.2167 |
| Heterogeneity (marked) | 0.94 | 0.7601 |
| Necrosis | 1.21 | 0.1932 |
| Distant Disease | 2.97 | 0.0021 |
*Diffusion status removed for missing >10%, AP x Trans and AP x CC for high correlation with AP, midbrain extension since it is included in the definition of extension beyond Pons or BP, extension beyond pons and brachium pontis due to correlation with extension beyond pons, enhancement subtypes due to correlation with enhancement, and hemorrhage with SWI or GRE sequences due to missing >10%).