Table 2.
a Dighe, Roos, Stricker Cycles | b FSD | FIE (FSD) | MaxDay | FIE (MaxDay) | c Transition Day |
---|---|---|---|---|---|
Dighe Mean cycles | −5 | 3.4 | −2 | 9.9 | 0 |
Dighe Upper 99% cycles | −5 | 3.5 | −2 | 9.5 | 0 |
Dighe Lower 99% cycles | −5 | 3.4 | −2 | 11.1 | 0 |
Roos Median cycles | −6 | 3.2 | −1 | 16.7 | 0 |
Roos 90th PCTL cycles | −4 | 2.5 | −2 | 12 | 0 |
Roos 10th PCTL cycles | −5 | 3.6 | −2 | 10.2 | 0 |
Stricker Mean cycles | −6 | 2.5 | −2 | 15 | 0 |
Stricker 95th PCTL cycles | −6 | 3.6 | −2 | 27.8 | 0 |
Stricker 5th PCTL cycles | −6 | 2.9 | −1 | 19.6 | 0 |
a Day-specific serum E2 levels with number of subjects and statistics are provided by Dighe et al. [18], Roos et al. [19], and Stricker et al. [20]. Their cycles are indexed to the serum LH peak (Day 0). b For calculation of the FIE values see Methods and Table 1. FSD is the first day of the cycle where FIE is ≥2.5 and validated by sequential increase rule. c The transition day is the day of indeterminate sign bracketed by change in sign from + to − with magnitude change >15.