AMPK	AMP-activated protein kinase;
ATF4	activating transcription factor 4;
ATF-6	activated transcription factor 6;
ATG	autophagy-related protein;
CHOP	C/EBP homologous protein;
eIF2α	eukaryote initiation factor 2α;
ER	endoplasmic reticulum;
ERAD	ER-associated protein degradation;
GBM	glioblastoma;
GGPP	geranylgeranyl pyrophosphate;
GRP78	glucose-related peptide 78 kD;
hATF	human atrial fibroblasts;
HMG–CoA	hydroxy-3-methyl-glutaryl–CoA;
IRE1	inositol-requiring enzyme 1α;
JNK	c-Jun N-terminal kinase;
LC3	microtubule-associated proteins light chain 3;
MEV	mevalonate;
MPG	methylpurine DNA glycosylase;
OEP	our experimental protocol;
PERK	protein kinase RNA-like ER kinase;
PERKi	PERK kinase activity inhibitor;
Simva	simvastatin;
TMZ	temozolomide;
UPR	unfolded protein response;
XBP-1s	x-box binding protein-1 spliced;