Table 1.
Baseline patient characteristics.
| Patient Characteristics | Total N = 1099 |
H and N 1 N = 72 |
Thorax N = 97 |
Abd. and R.P. 2 N = 106 |
Pelvis and Urogen. Org. 3 N = 28 |
Axial Skel. 4 N = 57 |
Upper Extr. 5 N = 116 |
Lower Extr. 5 N = 405 |
Breast N = 25 |
Skin N = 110 |
Other N = 83 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Gender, N (%), p < 0.001 | |||||||||||
| Male | 596 (54) | 41 (57) | 52 (54) | 57 (54) | 8 (29) | 35 (61) | 76 (66) | 218 (54) | 1 (4) | 64 (58) | 44 (53) |
| Female | 503 (46) | 31 (43) | 45 (46) | 49 (46) | 20 (71) | 22 (39) | 40 (34) | 187 (46) | 24 (96) | 46 (42) | 39 (47) |
| Age, Mean ± SD, p = 0.067 | |||||||||||
| (In years) | 60 ± 15 | 56 ± 15 | 60 ± 16 | 63 ± 13 | 63 ± 10 | 60 ± 17 | 62 ± 16 | 60 ± 15 | 66 ± 12 | 59 ± 16 | 59 ± 16 |
| Sarcoma Subtype *, N (%), p < 0.001 | |||||||||||
| STS 6 | 829 (75) | 35 (49) | 59 (61) | 102 (96) | 28 (100) | 1 (2) 18 | 85 (73) | 304 (75) | 25 (100) | 110 (100) | 80 (96) |
| BS 7 | 270 (25) | 37 (51) | 38 (39) | 4 (4) 17 | 0 (0) | 56 (98) | 31 (27) | 101 (25) | 0 (0) | 0 (0) | 3 (4) |
| Stage, N (%), p < 0.001 | |||||||||||
| I | 486 (44) | 24 (34) | 20 (21) | 52 (49) | 4 (14) | 20 (35) | 50 (43) | 176 (43) | 4 (16) | 95 (86) | 41 (50) |
| II | 315 (29) | 26 (36) | 42 (43) | 20 (19) | 1 (4) | 18 (32) | 41 (35) | 142 (35) | 3 (12) | 4 (4) | 18 (22) |
| III | 134 (12) | 1 (1) | 19 (20) | 21 (20) | 0 (0) | 0 (0) | 17 (15) | 60 (15) | 3 (12) | 1 (1) | 12 (14) |
| IV | 58 (5) | 8 (11) | 2 (2) | 7 (6) | 2 (7) | 12 (20) | 5 (4) | 14 (4) | 2 (8) | 1 (1) | 5 (6) |
| Missing | 106 (10) | 13 (18) | 14 (14) | 6 (6) | 21 (75) | 7 (13) | 3 (3) | 13 (3) | 13 (52) | 9 (8) | 7 (8) |
| Treatment, N (%), p < 0.000 | |||||||||||
| S 8 | 448 (41) | 15 (21) | 41 (43) | 47 (44) | 21 (75) | 21 (36) | 40 (34) | 131 (33) | 11 (44) | 94 (86) | 27 (33) |
| S and R 9 | 422 (38) | 29 (40) | 32 (33) | 26 (25) | 4 (14) | 18 (32) | 54 (47) | 195 (48) | 8 (32) | 10 (9) | 46 (55) |
| S and C 10 | 79 (7) | 9 (13) | 9 (9) | 12 (11) | 0 (0) | 3 (5) | 9 (8) | 33 (8) | 2 (8) | 1 (1) | 1 (1) |
| S, R and C 11 | 86 (8) | 8 (11) | 11 (11) | 12 (11) | 2 (7) | 5 (9) | 8 (7) | 33 (8) | 1 (4) | 0 (0) | 6 (7) |
| Missing | 64 (6) | 11 (15) | 4 (4) | 9 (9) | 1 (4) | 10 (18) | 5 (4) | 13 (3) | 3 (12) | 3 (4) | 3 (4) |
| Time since Diagnosis, Mean ± SD, p = 0.223 | |||||||||||
| (in months) | 67 ± 30 | 68 ± 30 | 64 ± 31 | 61 ± 26 | 67 ± 28 | 73 ± 30 | 69 ± 34 | 69 ± 31 | 58 ± 22 | 67 ± 30 | 67 ± 30 |
| Comorbidities, N (%), p = 0.050 | |||||||||||
| 0 | 369 (34) | 30 (42) | 28 (29) | 29 (28) | 5 (18) | 18 (32) | 31 (27) | 159 (40) | 4 (16) | 38 (34) | 27 (32) |
| 1 | 355 (32) | 17 (23) | 35 (36) | 30 (28) | 8 (28) | 23 (40) | 43 (37) | 123 (30) | 11 (44) | 37 (34) | 28 (34) |
| ≥2 | 375 (34) | 25 (35) | 34 (35) | 47 (44) | 15 (54) | 16 (28) | 42 (36) | 123 (30) | 10 (40) | 35 (32) | 28 (34) |
| Marital Status, N (%), p = 0.006 | |||||||||||
| Together 12 | 857 (78) | 55 (76) | 68 (70) | 81 (76) | 25 (89) | 42 (74) | 87 (75) | 335 (83) | 21 (84) | 90 (82) | 53 (64) |
| Single 13 | 240 (22) | 17 (24) | 29 (30) | 25 (24) | 3 (11) | 15 (26) | 27 (23) | 70 (17) | 4 (16) | 20 (18) | 30 (36) |
| Missing | 2 (0) | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 2 (2) | 0 (0) | 0 (0) | 0 (0) | 0 (0) |
| Education, N (%), p = 0.174 | |||||||||||
| No education 14 | 242 (22) | 8 (11) | 23 (24) | 23 (22) | 8 (29) | 17 (30) | 29 (25) | 90 (22) | 9 (36) | 20 (18) | 15 (18) |
| College 15 | 851 (77) | 63 (88) | 74 (76) | 82 (77) | 20 (71) | 40 (70) | 86 (74) | 313 (77) | 16 (64) | 90 (82) | 67 (81) |
| Missing | 6 (1) | 1 (1) | 0 (0) | 1 (1) | 0 (0) | 0 (0) | 1 (1) | 2 (1) | 0 (0) | 0 (0) | 1 (1) |
| Employment, N (%), p = 0.115 | |||||||||||
| Work 16 | 548 (50) | 40 (56) | 43 (44) | 46 (43) | 14 (50) | 28 (49) | 53 (46) | 205 (51) | 9 (36) | 62 (56) | 48 (58) |
| Other | 510 (46) | 26 (36) | 52 (54) | 56 (53) | 14 (50) | 26 (46) | 55 (47) | 191 (47) | 14 (56) | 43 (39) | 33 (40) |
| Missing | 41 (4) | 6 (8) | 2 (2) | 4 (4) | 0 (0) | 3 (5) | 8 (7) | 9 (2) | 2 (8) | 5 (5) | 2 (2) |
* Fisher exact not possible for tumor subtype; 1 H and N: Head and Neck; 2 Abd. and R.P: Abdominal including retroperitoneal; 3 Pelvis and urogen. org: Pelvis including urogenital organs; 4 Axial skel: Axial skeleton; 5 Extr: Extremities; 6 STS: Soft Tissue Sarcoma; 7 BS: Bone Sarcoma; 8 S: Surgery; 9 S andR: Surgery and radiotherapy; 10 S and C: Surgery and chemotherapy; 11 S, R and C: Surgery, radiotherapy and chemotherapy; 12 Married, civil partnership or cohabiting; 13 Single, widowed or divorced; 14 No education, primary, or secondary school; 15 Vocational, college, or university; 16 Employed or partially disabled; 17 Extra-skeletal osteosarcoma in the lower abdomen, Ewing sarcoma of the lower abdomen, Ewing sarcoma retroperitoneal, Ewing sarcoma of the kidney, categorized as BS based on histology; 18 Epithelioid angiosarcoma os ilium.