Figure 4.

Effect of HF diet supplemented with PA or LA on systemic insulin resistance (IR). Mice were intraperitoneally injected with insulin for insulin tolerance test (ITT, A) and glucose for glucose tolerance test (GTT) (C) and blood glucose was recorded at indicated time points (A,C). Area under the curve glucose values from ITT (B) and GTT (D) were determined. Values are expressed as mean ± SEM of 6–8 samples in each group. * p < 0.05, ^# p < 0.01, and ^ p < 0.001 versus CD. CD, chow diet; HF + PA, high fat + palmitic acid; HF + LA, high fat + lauric acid.