Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Phloretin’s inhibitory effect on the testosterone 6β-hydroxylation by CYP3A4 and HLMs. After preincubating phloretin with CYP3A4 (○) and HLMs (●) in the presence of NADPH for 5 min, testosterone (0.50 mM) was added to start the reaction. The reactions were terminated after 30 min. The formation of 6β-OH testosterone was measured by HPLC. Values represent the means ± SD of three determinations.
