Table 2.

Analysis of similarities (ANOSIM) at the OTU level using Bray-Curtis distance and Jaccard distance to assess the similarity of bacterial communities between groups at OTU level.

	OTUs Level (relative abundance rarefied)
Variable	D_Bray dissimilarity		D_Jaccard presence/absence
	Ra	p-value	Ra	p-value
IC/Non IC	−0.035	0.84	0.0009	0.46
C. difficile	−0.013	0.55	0.04	0.26
Gender	0.03	0.03*	0.01	0.13
Abx.last 3 m	−0.007	0.75	0.009	0.15
Abx.current	−0.08	1	0.01	0.31
Diarrhea	0.18	0.028*	0.13	0.085
Hospitalization	0.04	0.077	0.06	0.026*
PPI	0.27	0.003**	0.19	0.01*

^aCorrelation coefficient correlation coefficient.

^*P ≤ 0.05;

^**P ≤ 0.01.