Fig. 6 –

Summary of the main characteristics of the consensus classes. From top to bottom, the following characteristics are presented: proportion of consensus classes in the 1750 tumor samples; consensus class names; schematic graphical representation of tumor cells and their microenvironments (immune cells, fibroblasts, and smooth muscle cells); differentiation-based color scale showing features associated with consensus classes, including a luminal-to-basal gradient and neuroendocrine differentiation; and a table displaying the dominant characteristics such as oncogenic mechanisms, mutations, stromal infiltrate, immune infiltrate, histology, clinical characteristics, and median overall survival.

Ba/Sq = basal/squamous; LumNS = luminal nonspecified; LumP = luminal papillary; LumU = luminal unstable; MIBC = muscle-invasive bladder cancer; NE = neuroendocrine; NK = natural killer.