Figure 1.

Laminaria japonica water extract (LJWE) inhibits the expression of inflammatory chemokines in tumor necrosis factor (TNF)-α/interferon (IFN)-γ-stimulated HaCaT cells. (A) Cell viability in the presence of LJWE. The cells were treated with 0–200 μg/mL of LJWE with (+) or without (−) TNF-α/IFN-γ-stimulation for 24 h, and the cell viability was measured using the Cell Counting Kit-8 assay. (B) The inhibitory effects of LJWE on the overproduction of interleukin (IL)-8, regulated on activation normal T-cell expressed and secreted (RANTES), and thymus and activation-regulated chemokine (TARC). *** p < 0.001 vs. control treated with vehicle.