LJWE ameliorates atopic dermatitis (AD)-like skin lesions in NC/Nga mice. (A) Schematic representation of the experiment investigating the effect of LJWE on AD-like skin lesions induced by 2,4-dinitrochlorobenzene (DNCB). (B) Changes in the body weight, severity score of dermatitis, and trans-epidermal water loss (TEWL) during the experimental periods. (C) Inhibitory effects of LJWE on the overproduction of TARC, RANTES and IgE. Normal (no DNCB/vehicle); negative control (N.C., DNCB/vehicle); positive control (P.C., DNCB/5 mg/kg of prednisolone); low-dose LJWE (LJWE L; DNCB + 100 mg/kg per day of LJWE); high-dose LJWE (LJWE H; DNCB + 300 mg/kg per day of LJWE). All data are expressed as the mean ± standard error of the mean (SEM) (n = 7). * p < 0.05, ** p < 0.01, *** p < 0.001 versus N.C.