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. 2020 Oct 23;10(11):1472. doi: 10.3390/biom10111472

Figure 6.

Figure 6

Archaeal ribonucleotide excision repair. Embedded ribonucleotide monophosphates (rNMPs) are recognized and specifically excised by RNaseH2, resulting in one nucleotide gap with 3′-hydroxyl. Repair is concluded when DNA polymerase performs strand-displacement synthesis and the activities of flap endonuclease and DNA ligase remove the original strand and seal the resulting nick.