Figure 6.
Archaeal ribonucleotide excision repair. Embedded ribonucleotide monophosphates (rNMPs) are recognized and specifically excised by RNaseH2, resulting in one nucleotide gap with 3′-hydroxyl. Repair is concluded when DNA polymerase performs strand-displacement synthesis and the activities of flap endonuclease and DNA ligase remove the original strand and seal the resulting nick.
