Figure 2.

(A) Flow cytometry analysis on a bone marrow aspiration sample demonstrating CD34+/CD45^dim hematopoietic stem cells (HSC) (red color) (B) with normal CD123 expression pattern. (C) Combinatorial gating depicts various CD123^bright cells (green oval), which include CD34+ HSC elements and CD34− populations (gray), with only rare CD117+ cells (purple). (D) CD123^bright cells can be further subtyped into basophils (CD123^bright/HLA−DR−) and plasmacytoid dendritic cells (pDCs) (CD123^bright/HLA−DR+).