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. 2020 Oct 23;10(11):1474. doi: 10.3390/biom10111474

Figure 2.

Figure 2

TP53 mutations in biliary tract cancers (BTCs). (A) Frequency of TP53 mutations in different studies. (B) The frequency of TP53 mutations in subtypes of BTC. (C) Collective results of available datasets of TP53 mutation in BTCs. (D) Lollipop plots for tumor TP53 mutations in BTC patients. TP53 mutations frequently occur in the DNA binding domain of p53 (red region). Black, green, pink and blue dots indicate truncating, missense, in-frame and other mutations, respectively. When different mutation types occur at a single position, the color of the circle indicates the most frequent mutation type. TAD, transactivation domain; TD, tetramerization domain. Data were accessed at cBioPortal on 3 September 2020. Please add explanation for “+, −” in image.