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Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
Major events, namely oxidative stress and mitochondrial dysfunction, toxicity and aggregation of Aβ and tau, neuronal damage and apoptosis, memory loss and cognitive decline, characterizing the onset and progression of AD until death.