Table 7.
Influence of alginate:chitosan (w/w) mass ratio on alginate nanoparticle.
| Drug | Preparation Method | Mass Ratio | Particle Size (nm) | Encapsulation Efficiency (%) | Zeta Potential (mV) | Reference |
|---|---|---|---|---|---|---|
| Nisin | Ionic gelation | 8:2 | 40 | 15.9 | −45.6 | [145] |
| complexation | 472 | 15.1 | −29.8 | |||
| Curcumin diethyl disuccinate | Emulsification ionotropic gelation | 1:0.05 | 279 ± 71 | 38.7 ± 2.8 | −27.8 ± 0.3 | [180] |
| 1:0.15 | 434 ± 17 | 17.1 ± 2.3 | −19.8 ± 1.4 | |||
| Insulin | Alginate/chitosan core shell nanoformation | 3:1 | - | 63.0 | - | [91] |
| 3:2 | 71.0 | |||||
| 3:3 | 77.0 | |||||
| lovastatin | Ionic gelation | 6:3 | 900 ± 101 | - | - | [181] |
| 6.5:3 | 86 ± 3.7 | |||||
| 7:3 | 220 ± 17.5 | |||||
| - | Electrospray | 11:1 | 112 ± 35 | 0.42 ± 0.06 | - | [115] |
| 7:1 | 259 ± 68 | 0.34 ± 0.12 |