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. 2020 Oct 23;12(11):3091. doi: 10.3390/cancers12113091

Figure 5.

Figure 5

Functional category and network analyses of predictivity and descriptivity hit genes from Figure 4. (A) Distribution of functional categories enriched in shRNA and sgRNA hit genes. (B,C) Network analysis of common hit genes from shRNA and sgRNA analyses. Positive hit genes (HNF1B, IRS2, MDM2 and SATB2) are related to ‘neoplasia of cells’, and AGTR1 and KIF26A are related to ‘beta-arrestin-related protein’, while negative hit genes (CSF2, CDK9, GTF2F2 and HTATSF1) are related to ‘transcription of RNA’. The analyses were carried out using IPA software.