. 2020 Oct 23;18(11):524. doi: 10.3390/md18110524

Table 2.

Plasma content of the pharmacokinetic parameter C_Max (Maximum measured plasma concentration over the time span specified) for eicosapentaenoic acid (EPA), docosahexaenoic acid (DHA) and long chain-polyunsaturated fatty acids (n-3 LC-PUFA) after a single dose of frozen half-shell GSM, GSM food ingredient, GSM powder and GSM oil extract with matching levels of lipid for 12 and 48 h time points. ^a,b,c Geometric mean values across the column not sharing a common superscript were significantly different (p < 0.05) as determined by Fisher’s protected LSD.

	C_Max0–12h
		C_Max0–12h mg/L	95.0% Lower CL for Mean	95.0% Upper CL for Mean		C_Max0–12h mg/L	95.0% Lower CL for Mean	95.0% Upper CL for Mean		C_Max0–12h mg/L	95.0% Lower CL for Mean	95.0% Upper CL for Mean
Frozen half-shell GSM	EPA	546.6^c	441.4	676.9	DHA	851	747.8	967.3	n-3 LC PUFA	1694	1578.5	1818.5
GSM Food ingredient		474.4 ^a,b	359.7	625.7		834	724.1	959.3		1681	1439.6	1961.9
GSM Powder		539.0 ^b,c	405.7	716		736	640.2	845.5		1659	1434	1918.5
GSM Oil extract		450.4 ^a	372.1	545.1		780	711.2	855.6		1604.5	1414.2	1820.9
F		5.045	-	-		−	-	-		−	-	-
p-value		0.011	-	-		−	-	-		−	-	-
	C_Max48h
		C_Max0–48h mg/L	95.0% Lower CL for Mean	95.0% Upper CL for Mean		C_Max0–48h mg/L	95.0% Lower CL for Mean	95.0% Upper CL for Mean		C_Max0–48h mg/L	95.0% Lower CL for Mean	95.0% Upper CL for Mean
Frozen half-shell GSM	EPA	594.7 ^c	499.8	707.5	DHA	857	759.2	968.4	n-3 LC PUFA	1772	1623.6	1934
GSM Food ingredient		536.8 ^a,b	421.5	683.7		852	749.1	968		1782	1509.3	2103.4
GSM Powder		593.3 ^b,c	445.5	790.2		835	703.6	992		1832	1504.6	2230.6
GSM Oil extract		477.4 ^a	395.1	576.8		806	713.9	909.2		1634	1431.5	1864.7
F		6.388	-	-		−	-	-		−	-	-
p-value		0.004	-	-		−	-	-		−	-	-