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. 2020 Oct 23;12(11):3092. doi: 10.3390/cancers12113092

Figure 2.

Figure 2

Histopathologic presentation of six cases of rare primary malignant bone sarcomas (A) spindle cell sarcoma of bone: tumor cells are typically organized in a fascicular or herringbone pattern; (B) angiosarcoma of bone: tumor is composed of a markedly atypical, predominantly solid epithelioid cell proliferation, featuring abundant eosinophilic cytoplasm, often harboring macronucleolated vescicular nuclei; (C–E) round cell sarcomas; (C) CIC-DUX4; (D) undifferentiated round cells sarcoma; (E) BCOR-CCNB3; (F) solitary fibrous tumor of bone with a classic hemangiopericytomatous pattern. (100× of magnification; haematoxylin and eosin staining).