Figure 1.

Effect of circadian rhythm disruption on body health. Circadian alignment is associated with wellness and body health. Circadian clock malfunctioning induced by genetic factors (clock gene mutations) and/or environmental factors (inappropriate light exposure, sleep restriction, jetlag, shift work, irregular food intake) can lead to the development of several disorders including cancer, diabetes, cardiovascular disorders, endocrine diseases, inflammation, mental disorders, immune system alterations and reproductive disorders.