Table 2.
Characteristics of participants stratified by rs3751812 genotypes.
| rs3751812 | G/G | G/T | T/T | p-Value * |
|---|---|---|---|---|
| N | 211 | 420 | 181 | |
| Genotype frequency | 0.26 | 0.52 | 0.22 | >0.05 |
| Age | 40.5 (14.2) | 41.2 (14.7) | 39.5 (14.3) | 0.33 |
| Female (%) | 53.8% (0.49) | 53.8% (0.50) | 47.8% (0.50) | 0.36 |
| BMI (kg/m2) | 27.6 (6.0) | 28.7 (6.8) | 28.9 (6.8) | 0.060 |
| <25.0 | 81 (38.8%) | 136 (32.9%) | 53 (29.9%) | 0.410 |
| 25.0–29.9 | 69 (33.0%) | 141 (34.1%) | 66 (37.3%) | |
| ≥30.0 | 59 (28.2%) | 136 (32.9%) | 58 (32.8%) | |
| Total body fat content (kg) | 25.3 (12.4) | 27.6 (13.8) | 28.2 (15.2) | 0.080 |
| Total body fat content (%) | 30.6 (9.1) | 31.8 (9.6) | 31.6 (10.3) | 0.377 |
| Waist circumference (cm) | 94.3 (17.5) | 96.7 (17.2) | 97.5 (16.7) | 0.054 |
| Hip circumference (cm) | 101.3 (12.4) | 104.2 (13.0) | 103.8 (12.5) | 0.008 |
| WHR | 0.927 (0.091) | 0.925 (0.088) | 0.937 (0.085) | 0.327 |
| Visceral fat (cm3) | 103.0 (81.0) | 110.0 (79.9) | 112.3 (83.0) | 0.379 |
| Visceral fat (%) | 36.4 (11.8) | 37.5 (12.4) | 37.2 (11.7) | 0.587 |
| Subcutaneous fat (cm3) | 163.5 (83.1) | 167.2 (80.5) | 175.0 (82.7) | 0.401 |
| Subcutaneous fat (%) | 63.7 (11.7) | 62.3 (12.9) | 62.8 (11.7) | 0.557 |
| Visceral/subcutaneous fat ratio | 0.642 (0.406) | 0.687 (0.475) | 0.665 (0.413) | 0.554 |
| Total cholesterol | 202.7 (56.0) | 191.7 (41.3) | 194.0 (43.2) | 0.070 |
| HDL | 60.7 (14.1) | 59.8 (15.6) | 59.5 (14.5) | 0.662 |
| LDL | 117.3 (43.3) | 109.4 (37.8) | 111.2 (41.8) | 0.095 |
| TG | 123.8 (143.9) | 111.9 (69.7) | 116.3 (61.9) | 0.289 |
| Blood glucose level during OGTT (mg/dL) | ||||
| 0 min | 96.8 (24.1) | 95.6 (18.3) | 97.1 (20.8) | 0.914 |
| 30 min | 147.0 (44.3) | 145.0 (31.6) | 150.1 (35.6) | 0.312 |
| 60 min | 132.3 (56.0) | 129.5 (46.3) | 134.2 (46.3) | 0.380 |
| 120 min | 100.7 (46.1) | 99.1 (32.1) | 98.8 (31.0) | 0.621 |
| History of prediabetes or diabetes | ||||
| Yes | 103 (48.8%) | 209 (49.8%) | 95 (52.5%) | 0.751 |
| No | 108 (51.2%) | 211 (50.2%) | 86 (47.5%) | |
| Dietary assessment (n) | 126 | 259 | 101 | |
| Daily energy intake (kcal) | 1807.2 (732.3) | 1766.9 (676.0) | 1837.4 (713.4) | 0.849 |
| Daily energy from protein (%) | 18.7 (4.4) | 19.0 (4.9) | 19.1 (4.9) | 0.901 |
| Daily energy from fat (%) | 31.2 (7.2) | 30.9 (7.5) | 31.9 (7.8) | 0.568 |
| Daily energy from carbohydrates (%) | 47.6 (7.7) | 47.8 (9.1) | 46.8 (8.5) | 0.662 |
| Daily physical activity level | ||||
| Low | 16 (7.6%) | 25 (6.0%) | 18 (9.9%) | 0.302 |
| Moderate | 50 (23.7%) | 83 (19.8%) | 40 (22.1%) | |
| High | 145 (68.7%) | 312 (74.3%) | 123 (68.0%) | |
Data presented as mean and standard deviation (SD), number of observations, and frequency. BMI, body mass index; HDL, high-density lipoprotein; LDL, low-density lipoprotein; OGTT, oral glucose tolerance test; TG, triglycerides; WHR, waist-hip ratio. * Holm-adjusted Kruskal-Wallis/ANOVA p-values.