Table 3.
Characteristics of participants stratified by rs8050136 genotypes.
| rs8050136 | C/C | A/C | A/A | p-Value * |
|---|---|---|---|---|
| N | 209 | 424 | 182 | |
| Genotype frequency | 0.26 | 0.52 | 0.22 | >0.05 |
| Age | 40.2 (14.1) | 41.3 (14.8) | 39.4 (14.3) | 0.24 |
| Females (%) | 54.3% (0.49) | 53.4% (0.49) | 47.7% (0.50) | 0.36 |
| BMI (kg/m2) | 27.6 (6.1) | 28.7 (6.8) | 28.9 (6.8) | 0.063 |
| <25.0 | 80 (38.6%) | 138 (33.2%) | 54 (30.2%) | 0.422 |
| 25.0–29.9 | 69 (33.3%) | 140 (33.7%) | 67 (37.4%) | |
| ≥30.0 | 58 (28.0%) | 138 (33.2%) | 58 (32.4%) | |
| Total body fat content (kg) | 25.3 (12.4) | 27.5 (13.8) | 28.2 (15.2) | 0.095 |
| Total body fat content (%) | 30.6 (9.1) | 31.8 (9.6) | 31.6 (10.4) | 0.465 |
| Waist circumference (cm) | 94.2 (17.6) | 96.7 (17.2) | 97.4 (16.6) | 0.053 |
| Hip circumference (cm) | 101.2 (12.5) | 104.1 (13.0) | 103.8 (12.4) | 0.008 |
| WHR | 0.927 (0.092) | 0.925 (0.088) | 0.936 (0.085) | 0.382 |
| Visceral fat (cm3) | 103.3 (81.5) | 110.2 (80.0) | 111.8 (82.5) | 0.381 |
| Visceral fat (%) | 36.4 (11.7) | 37.6 (12.5) | 37.1 (11.6) | 0.570 |
| Subcutaneous fat (cm3) | 163.7 (83.5) | 166.9 (80.8) | 175.3 (83.1) | 0.405 |
| Subcutaneous fat (%) | 63.7 (11.6) | 62.2 (13.0) | 62.9 (11.6) | 0.540 |
| Visceral/subcutaneous fat ratio | 0.641 (0.404) | 0.690 (0.477) | 0.662 (0.410) | 0.536 |
| Total cholesterol | 201.9 (56.1) | 192.1 (41.4) | 193.7 (43.1) | 0.153 |
| HDL | 60.8 (14.0) | 59.6 (15.7) | 59.7 (14.4) | 0.422 |
| LDL | 116.3 (43.3) | 109.9 (37.9) | 111.1 (41.8) | 0.189 |
| TG | 124.1 (144.3) | 113.2 (71.1) | 115.1 (61.3) | 0.491 |
| Blood glucose level during OGTT (mg/dL) | ||||
| 0 min | 96.8 (24.2) | 95.8 (18.5) | 96.8 (20.4) | 0.922 |
| 30 min | 146.6 (44.5) | 145.2 (31.7) | 150.1 (35.4) | 0.263 |
| 60 min | 131.7 (56.4) | 129.9 (46.1) | 133.9 (46.1) | 0.413 |
| 120 min | 100.2 (46.3) | 99.3 (32.2) | 98.6 (30.9) | 0.493 |
| History of prediabetes or diabetes | ||||
| Yes | 100 (47.8%) | 213 (50.2%) | 96 (52.7%) | 0.628 |
| No | 109 (52.2%) | 211 (49.8%) | 86 (47.3%) | |
| Dietary assessment (n) | 103 | 264 | 123 | |
| Daily energy intake (kcal) | 1820.5 (734.9) | 1759.6 (673.3) | 1853.9 (716.3) | 0.645 |
| Daily energy from protein (%) | 18.7 (4.5) | 19.0 (4.9) | 19.0 (4.9) | 0.855 |
| Daily energy from fat (%) | 31.2 (7.2) | 30.9 (7.5) | 31.9 (7.8) | 0.506 |
| Daily energy from carbohydrates (%) | 47.6 (7.7) | 47.9 (9.1) | 46.8 (8.4) | 0.572 |
| Daily physical activity level | ||||
| Low | 16 (7.7%) | 25 (5.9%) | 19 (10.4%) | 0.179 |
| Moderate | 50 (23.9%) | 83 (19.6%) | 40 (22.0%) | |
| High | 143 (68.4%) | 316 (74.5%) | 123 (67.6%) | |
Data presented as mean and standard deviation (SD), number of observations, and frequency. BMI, body mass index; HDL, high-density lipoprotein; LDL, low-density lipoprotein; OGTT, oral glucose tolerance test; TG, triglycerides; WHR, waist-hip ratio. * Holm-adjusted Kruskal-Wallis/ANOVA p-values.