Table 4.
Characteristics of participants stratified by rs8044769 genotypes.
| rs8044769 | C/C | C/T | T/T | p-Value * |
|---|---|---|---|---|
| N | 270 | 406 | 138 | |
| Genotype frequency | 0.33 | 0.50 | 0.17 | >0.05 |
| Age | 40.4 (14.8) | 41.2 (14.6) | 39.6 (13.7) | 0.54 |
| Females (%) | 51.8% (0.50) | 51.9% (0.50) | 56.2% (0.49) | 0.65 |
| BMI (kg/m2) | 28.5 (6.8) | 28.7 (6.7) | 27.8 (6.1) | 0.534 |
| <25.0 | 88 (33.2%) | 131 (32.8%) | 51 (37.5%) | 0.862 |
| 25.0–29.9 (kg/m2) | 92 (34.7%) | 143 (35.8%) | 43 (31.6%) | |
| ≥30.0 (kg/m2) | 85 (32.1%) | 126 (31.5%) | 42 (30.9%) | |
| Total body fat content (kg) | 27.7 (15.0) | 27.2 (13.6) | 25.8 (11.9) | 0.676 |
| Total body fat content (%) | 31.7 (10.1) | 31.4 (9.6) | 31.1 (9.0) | 0.893 |
| Waist circumference (cm) | 96.2 (17.2) | 96.8 (17.3) | 94.6 (16.8) | 0.429 |
| Hip circumference (cm) | 103.3 (12.6) | 104.0 (13.0) | 101.5 (12.2) | 0.189 |
| WHR | 0.928 (0.089) | 0.927 (0.088) | 0.929 (0.089) | 0.980 |
| Visceral fat (cm3) | 109.2 (78.3) | 110.3 (83.7) | 99.8 (72.5) | 0.648 |
| Visceral fat (%) | 37.7 (11.8) | 36.9 (12.3) | 36.4 (12.0) | 0.617 |
| Subcutaneous fat (cm3) | 168.6 (83.3) | 169.7 (82.4) | 160.9 (74.2) | 0.773 |
| Subcutaneous fat (%) | 62.3 (11.8) | 63.0 (12.8) | 63.7 (11.8) | 0.598 |
| Visceral/subcutaneous fat ratio | 0.689 (0.492) | 0.662 (0.421) | 0.641 (0.408) | 0.590 |
| Total cholesterol | 193.8 (40.1) | 191.7 (42.7) | 206.7 (62.7) | 0.029 |
| LDL | 111.0 (38.6) | 109.6 (38.7) | 119.8 (46.5) | 0.058 |
| HDL | 60.7 (14.7) | 59.2 (15.5) | 60.4 (13.8) | 0.176 |
| TG | 110.5 (58.7) | 114.6 (73.4) | 132.6 (170.6) | 0.689 |
| Blood glucose level during OGTT (mg/dL) | ||||
| 0 min | 96.6 (20.0) | 96.1 (21.0) | 96.0 (20.1) | 0.910 |
| 30 min | 149.6 (35.1) | 143.7 (32.0) | 148.8 (47.8) | 0.229 |
| 60 min | 133.3 (45.4) | 128.7 (47.3) | 133.5 (59.3) | 0.303 |
| 120 min | 98.6 (31.8) | 99.3 (30.7) | 100.6 (53.0) | 0.147 |
| History of prediabetes or diabetes | ||||
| Yes | 143 (53.0%) | 201 (49.5%) | 64 (46.4%) | 0.420 |
| No | 127 (47.0%) | 205 (50.5%) | 74 (53.6%) | |
| Dietary assessment (n) | 157 | 248 | 83 | |
| Daily energy intake (kcal) | 1775.7 (646.2) | 1792.7 (735.8) | 1816.0 (686.3) | 0.791 |
| % of daily energy from protein | 18.9 (4.8) | 19.2 (5.0) | 18.4 (4.1) | 0.608 |
| % of daily energy from fat | 32.5 (7.3) | 30.1 (7.5) | 31.9 (7.4) | 0.005 |
| % of daily energy from carbohydrates | 46.5 (8.5) | 48.3 (8.9) | 47.1 (8.1) | 0.164 |
| Daily physical activity level | ||||
| Low | 23 (8.5%) | 26 (6.4%) | 10 (7.2%) | 0.060 |
| Moderate | 55 (20.4%) | 77 (19.0%) | 41 (29.7%) | |
| High | 192 (71.1%) | 303 (74.6%) | 87 (63.0%) | |
Data presented as mean and standard deviation (SD), number of observations, and frequency. BMI, body mass index; HDL, high-density lipoprotein; LDL, low-density lipoprotein; OGTT, oral glucose tolerance test; TG, triglycerides; WHR, waist-hip ratio. * Holm-adjusted Kruskal-Wallis/ANOVA p-values.