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. 2020 Oct 23;12(11):3103. doi: 10.3390/cancers12113103

Table 3.

Summary of clinical trials conducted to examine the effect of time-of-day adjusted cancer treatment.

Type of Cancer Type of Intervention: Reference
Brain metastasis in non-small-cell lung carcinoma Radiosurgery [101,102]
Multiple brain metastases Radiotherapy [103]
Breast cancer Radiotherapy [104]
Breast carcinoma, hepatocellular carcinoma, Cholangiocarcinoma Chemotherapy [105]
Painful bone metastases Radiotherapy [106]
Cervical carcinoma Radiotherapy [107]
Colorectal Chemotherapy [5,6,98,108,109,110]
Head and neck Radiotherapy [111,112]
Oral squamous cell carcinoma Chemotherapy [113]
Prostate adenocarcinoma Radiotherapy [114]
Soft tissue, bone sarcoma Chemotherapy [115]
Nasopharyngeal carcinoma Chemotherapy [116,117,118]
Non-small-cell lung carcinoma Chemotherapy [119]
High-grade glioma Chemotherapy [120]