Coronavirus family genome diversity and conserved features. The coronavirus family whole-genome phylogeny, with different genera and sublineages represented, is provided on the left. Each row corresponds to a different coronavirus family member annotated with host, genus, collection location, year, and the isolate name. The CoV names are color coded to indicate host species (red, human; blue, bat, civet, camel; green, bird). The columns on the right correspond to gene products and UTR features along the length of the coronavirus genomes, with each feature normalized to the same column width. The color intensities indicate the degree of nucleotide and amino acid conservation (i.e., sequence identity) with respect to the SARS-CoV-2 reference genome (NCBI RefSeq genome accession no. NC_045512.2).