Table 1.
Characteristics of study subjects.
| HC group (n = 17) | AHE group (n = 17) | HEV-ALF group (n = 17) | P value | |
|---|---|---|---|---|
| Age (y) | 43.4 ± 14.9 | 45.7 ± 15.3 | 55.8 ± 7.3 | 0.018 |
| Gender (F/M) | 9/8 | 7/10 | 3/14 | 0.095 |
| Pregnant woman | 0 | 0 | 0 | — |
| Fever | 0 | 4 (23.53) | 7 (41.18) | 0.014 |
| Jaundice | 0 | 15 (88.24) | 17 (100.00) | ≤0.001 |
| Nausea/vomit | 0 | 5 (29.41) | 9 (52.94) | 0.002 |
| Severity of hepatic encephalopathy | 0 | 0 | 4 (23.53) | 0.013 |
| Hepatorenal syndrome | 0 | 2 (11.76) | 1 (5.88) | 0.352 |
| Ascites | 0 | 2 (11.76) | 8 (47.06) | ≤0.001 |
| IgM(+) | 0 | 17 (100.00) | 17 (100.00) | ≤0.001 |
| HEV-RNA (IU/ml) | 0 | 34.84 (29.18-38.73) | 33.44 (30.55-37.74) | ≤0.001 |
| ALT (U/l) | 18 (9-31) | 535 (128-834) | 750 (392-1027) | ≤0.001 |
| TBIL (μmol/l) | 12.4 (8.4-14.2) | 58.0 (12.2-141.6) | 206.6 (92.0-263.4) | ≤0.001 |
| Length of stay (day) | 0 | 7 (5-11) | 12 (8-23) | ≤0.001 |
| Mortality rate | 0 | 0 | 8 (47.06) | ≤0.001 |
The P value was for the difference among the three groups.