Table 2.
Changes in Scores of PROs in Patients with HCV Infection from the Beginning of Treatment to 3 Years Later.
| Start of DAA | 3 years later | p value | ||||
|---|---|---|---|---|---|---|
| CSS | 6.2 (4.158) | 5.13 (4.032) | 0.0084 | |||
| K-6 | 2.36 (2.993) | 2.03 (3.483) | 0.3311 | |||
| PD in K-6 | 2 | 3 | 1 | |||
| ESS | 3.51 (83.189) | 3.56 (3.295) | 0.8509 | |||
| PSQI | 6.89 (3.256) | 6.3 (2.721) | 0.0391 | |||
| RLS | 13 | 9 | 0.4986 | |||
| SF-36:PFN | 43.6 (12.614) | 42.47 (14.824) | 0.3599 | |||
| SF-36:RPN | 43.78 (12.24) | 45.03 (12.28) | 0.378 | |||
| SF-36:BPN | 48.87 (10.9) | 48.99 (10.61) | 0.8163 | |||
| SF-36:GHN | 43.54 (89.09) | 47.35 (8.08) | <0.0001 | |||
| SF-36:VTN | 48.6 (10.97) | 49.25 (9.6) | 0.5487 | |||
| SF-36:SFN | 47.15 (11.234) | 49.19 (9.49) | 0.0996 | |||
| SF-36:REN | 45.22 (12.59) | 47.12 (12.1) | 0.1311 | |||
| SF-36:MHN | 50.75 (9.43) | 49.21 (9.14) | 0.1571 | |||
| SF-36:PCS | 43.11 (12.53) | 43.49 (12.73) | 0.6908 | |||
| SF-36:MCS | 50.9 (8.831) | 51.87 (8.387) | 0.3278 | |||
| SF-36:RCS | 47.36 (12.06) | 48.19 (11.55) | 0.6383 |
Data are presented as mean (SD).
CSS: Cirrhosis-related symptom score, ESS: Epworth sleepiness score, K-6: Kessler 6 score, PRO: patient-reported outcome, PSQI: Pittsburgh sleep quality index, BPN: bodily pain, SF-36, GHN: general health, MCS: mental component summary, MHN: mental health, NS: not significant, PCS: physical component summary, PFN: physical functioning, RCS: role/social component summary, REN: role emotional, RPN: role physical, SFN: social functioning, VTN: vitality, RLS: restless legs syndrome, PD: psychological distress