Table 1.
Demographics and Indications
| Variables | PCC3 (n = 57) | PCC4 (n = 23) |
|---|---|---|
| Characteristics | ||
| Age (years)a | 74.0 (62.0–80.0) | 66.0 (57.0–82.0) |
| Weight (kg)a | 81.4 (72.1–94.4) | 77.8 (64.7–97.8) |
| Sex, n (%) | ||
| Male | 36 (63.2%) | 12 (52.2%) |
| Female | 21 (36.8%) | 11 (47.8%) |
| Indication for warfarin, n (%) | ||
| Atrial Arrhythmias | 32 (56.1%) | 8 (34.8%) |
| DVT/PEb | 7 (12.8%) | 4 (17.4%) |
| Valve replacement | 6 (10.5%) | 5 (21.7%) |
| Ischemia CVA | 4 (7.0%) | 1 (4.3%) |
| Other | 8 (14.0%) | 5 (21.7%) |
| Bleed type, n (%) | ||
| Intracranial | 31 (54.4%) | 19 (82.6%) |
| Gastrointestinal | 10 (17.5%) | 2 (8.7%) |
| Other | 16 (28.1%) | 2 (8.7%) |
CVA cerebrovascular accident, DVT/PE deep vein thrombosis and/or pulmonary embolism, EWR emergent warfarin reversal, PCC3 3-factor prothrombin complex concentrate, PCC4 4-factor prothrombin complex concentrate
aAge and Weight given as median (25th–75th percentiles)
bProphylaxis or treatment