Table 3.

Summary of relationships and level of evidence for sedentary behaviour and each health outcome in adults

Health Outcomes	Evidence for association	Evidence for dose-response c	Evidence for variation in association by physical activity	Evidence for type or domain of sedentary behaviour
All-cause mortality	Moderate	Moderate	Moderate	Insufficient
CVD mortality	Moderate	Moderate	Moderate	Insufficient
Cancer mortality	Moderate	Moderate	Moderate	Insufficient
Incident type 2 diabetes	Moderate	Low	Insufficient	Insufficient
Incident CVD	Moderate	Moderate	Insufficient	Insufficient
Incident cancer a	Low-moderate b	Low	Insufficient	Insufficient
Adiposity	Low/insufficient	Low/insufficient	Insufficient	Insufficient

See the WHO report [16] for details on the framework to rate the certainty of the evidence and the full evidence profiles

^a Includes endometrial, colon, and lung cancers. Evidence graded very low to low certainty for other cancer types

^b Level of evidence rating based on evidence from PAGAC reviews [9]

^c It was concluded that there was insufficient evidence to set quantified (time-based) recommendations