The Expression of miR-10a in Blood, Synovium, and FLSs of OA
(A) The expression of miR-10a in blood from OA patients (n = 30) and healthy controls (n = 22). (B) The expression of miR-10a in synovium from OA patients (n = 12) and controls (n = 3). (C) The localization of miR-10a in the synovium from OA patients (n = 3) and controls (n = 3). (D) The correlation (Pearson’s correlation coefficient) of miR-10a expression and OA severity (n = 25). (E) The response of miR-10a to IL-1β (10 ng/mL) and TNF-α (20 ng/mL) treatment in OA-FLSs for 48 h (n = 6). Data represent means ± SEM; ∗p < 0.05, ∗∗p < 0.01, ∗∗∗p < 0.001, as determined by Student’s t test.