Table 1.
Effect of DNMT1 Depletion in Blattella germanica Embryos on CG Methylation Levels in Different Gene Regions
| Gene Region | Control | DNMT1-Depleted | Decrease (%) |
|---|---|---|---|
| All regions | 17.8 | 8.8 | 50.5 |
| Intergenic regions | 10.0 | 5.2 | 47.5 |
| Promoter region | 26.4 | 10.9 | 58.7 |
| Gene | 41.8 | 19.1 | 54.2 |
| 5′ UTR | 27.4 | 11.0 | 60.0 |
| All exons | 51.3 | 21.5 | 58.0 |
| First exon | 20.5 | 7.4 | 63.8 |
| Other exons | 62.7 | 27.2 | 56.7 |
| Last exon | 59.2 | 28.9 | 51.1 |
| Exon of monoexonic | 30.9 | 8.1 | 73.7 |
| All introns | 40.6 | 18.9 | 53.5 |
| First intron | 30.3 | 13.1 | 56.9 |
| Other introns | 45.8 | 21.4 | 53.2 |
| Last intron | 41.0 | 19.5 | 52.5 |
| Intron of monointronic | 23.3 | 11.3 | 51.3 |
| 3′UTR | 75.5 | 36.2 | 52.1 |
Measurements were taken on 4-day-old embryos, in controls and in DNMT1-depleted Insects. Results are expressed as a percentage of methylated CG.