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. 2020 Nov 13;11:570888. doi: 10.3389/fimmu.2020.570888

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Copyright © 2020 Zu, Yao, Song, Cui, Guan, Chen, Zhen and Li

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Unchanged cTfh cells and altered Ig profile in sporotrichosis patients. (A) Statistical graphs in the upper row were for CD4⁺CXCR5⁺Tfh while the lower row were for CD4⁺CXCR5⁺PD1⁺Tfh. The comparison of cTfh percentages were between HC (n = 24) and whole patients (n = 50), patients with different duration (< 6 mon, n = 24; > 6 mon, n = 26) and clinical types (FF, n = 33; LF, n = 17). (B) Comparison of serum levels of total IgG, IgM, and IgE between patients (n = 46) and HC (n = 24). (C, D) Distribution of IgG subtypes (IgG1, IgG2, and IgG3 and IgG4) in patients (in whole: n = 20; SD: n = 7; LD: n = 13) and HC (n = 19). Error bars represent mean±SD. *P < 0.05, **P < 0.01, and NS P ≥ 0.05.