Table 1.
Demographics, questionnaires and clinical factors of participants.
| All | Responder | Non-responder | |||||||
|---|---|---|---|---|---|---|---|---|---|
| n | S.D. | n | S.D. | n | S.D. | ||||
| n | 22.0 | 8.0 | 14.0 | ||||||
| Mean age, years | 39.5 | 11.5 | 38.0 | 14.6 | 40.3 | 9.9 | |||
| Gender | |||||||||
| Male | 9.0 | 5.0 | 4.0 | ||||||
| Female | 13.0 | 3.0 | 10.0 | ||||||
| Mean depression and anxiety scores | |||||||||
| BDI T1 | 22 | 27.0 | 8.0 | 8 | 30.0 | 7.3 | 14 | 25.2 | 8.2 |
| BDI T6 | 22 | 18.4 | 12.0 | 8 | 8.5 | 4.3 | 14 | 24.1 | 11.2 |
| HAM-D T1 | 22 | 25.5 | 6.1 | 8 | 26.3 | 4.5 | 14 | 25 | 6.9 |
| HAM-D T6 | 22 | 18.1 | 10.1 | 8 | 8.3 | 5.7 | 14 | 23.6 | 9.1 |
| MADRS T1 | 22 | 28.6 | 7.4 | 8 | 30.5 | 7.3 | 14 | 27.6 | 7.6 |
| MADRS T6 | 21 | 20.4 | 10.1 | 7 | 9.9 | 3.7 | 14 | 25.7 | 7.7 |
| Chronology and clinical factors | |||||||||
| First episode of MDD | 16 | 72.7% | 5 | 62.5% | 11 | 78.6% | |||
| Recurring MDD (average previous episodes) | 6 | 27.3% (2.3) | 3 | 37.5% (1.7) | 3 | 21.3% (3) | |||
| Duration of current episode, mean(SD) | 22 | 3 weeks (1.3) | 8 | 2.9 weeks (1.1) | 14 | 3 weeks (1.8) | |||
| Positive family history | 7 | 31.8% | 2 | 25% | 5 | 35% | |||
| Psychosocial strain | 3 | 13.6% | 2 | 25% | 1 | 7% | |||
| Outpatient | 15 | 68.2% | 5 | 62.5% | 10 | 71.4% | |||
| Inpatient | 7 | 31.8% | 3 | 37.5% | 4 | 28.6% | |||
S.D., Standard deviation; n, number of participants; BDI, Beck Depression inventory; HAM-D, Hamilton Depression scale; MADRS, Montgomery–Åsberg Depression Rating Scale Indicated are demographical facts, mean questionnaire scores as well as chronology and various clinical factors of all participants, as well as divided into subgroups of responders and non-responders. Positive family history refers to a first-degree relative with MDD. Psychosocial strain refers to exceptional events or stressful periods preceding symptoms. Out- and inpatient treatment refers to the time-period of the study only. There were no significant differences between the two groups concerning chronology and clinical factors.