Table 2.
Correlation analysis: activity in regions of interest significantly associated with change in BDI.
| Anatomic region | BA | Cluster size | x | y | z | r | p | r (BDI T1) |
|---|---|---|---|---|---|---|---|---|
| Positive >neutral | ||||||||
| Posterior cingulate cortex R>L | 23 | 2,356 | 6 | −37 | 25 | 0.8807 | 0.000000 | 0.25 |
| Middle frontal gyrus L>R | 9 | 974 | −9 | 50 | 25 | 0.8360 | 0.000001 | 0.29 |
| Thalamus R | 221 | 3 | −10 | 16 | 0.8173 | 0.000003 | 0.15 | |
| Middle temporal gyrus R | 39 | 1,697 | 48 | −58 | 25 | 0.8615 | 0.000000 | 0.29 |
| Negative >neutral | ||||||||
| Thalamus L | 1,220 | −18 | −22 | 1 | 0.6635 | 0.000761 | 0.54 (0.009) | |
| Posterior cingulate cortex L>R | 29 | 1,294 | −6 | −46 | 10 | 0.7064 | 0.000239 | 0.33 |
| Hippocampus R | 976 | 30 | −31 | −8 | 0.652 | 0.001010 | 0.49 (0.022) | |
| Anterior cingulate cortex R = L | 32 | 1,104 | 12 | 32 | 28 | 0.6626 | 0.000779 | 0.13 |
BA, Brodmann area; r, Pearson's correlation coefficient; p where significant, BDI T1, pre-treatment BDI. Activated regions according to the whole brain correlation analysis in the contrasts positive>neutral and negative>neutral. Indicated is the cluster size of each region in voxels, the Tailarach coordinates (x, y, z) of the peak activation of the cluster, and Pearson's correlation coefficient between change in BDI and beta values, as well as the corresponding p-value. The thalamic region in contrast positive>neutral corresponds to the medial dorsal nucleus, and in contrast negative>neutral to the ventral posterior lateral nucleus. The anterior cingulate cortex refers specifically to the pregenual anterior cingulate. The correlation coefficient r is printed in bold when significant.