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. 2020 Nov 11;5(11):1057–1069. doi: 10.1016/j.jacbts.2020.08.011

Figure 6.

Figure 6

Effect of TRV027 on the Cardiac Contractility of Model Mice of Human Congenital DCM

(A) The representative hearts of wild-type (WT) mouse and model mouse of human congenital dilated cardiomyopathy (cTnTΔK210) at postnatal day 6 (P6). (B) Representative M-mode ultrasound cardiogram of wild-type and cTnTΔK210 mice 2 h after administration of saline or TRV027 (3 mg/kg). (C) Ejection fraction (EF) in each condition. Statistical significance was analyzed with 1-way analysis of variance followed by Tukey’s test. n = 5 in each group.