Table 1.
Demographic and clinical characteristics of patients with obsessive–compulsive disorder (OCD) and healthy controls (HCs) at baseline and follow-up.
| OCD (N = 17) | HC (N = 21) | Statistical analysis | p | |||
|---|---|---|---|---|---|---|
| χ2 or Ta | ||||||
| Sex (male/female) | 12/5 | 11/10 | 1.304 | 0.254 | ||
| Handedness (left/right) | 1/16 | 3/18 | 0.704 | 0.401 | ||
| Age (years) | 26.4 ± 6.0 | 26.0 ± 5.3 | 0.225 | 0.823 | ||
| Education years (years) | 14.3 ± 2.2 | 15.4 ± 1.7 | − 1.772 | 0.085 | ||
| IQ | 112.4 ± 9.6 | 113.5 ± 10.8 | − 0.331 | 0.742 | ||
| Age of onset (years) | 16.6 ± 6.03 | – | – | – | ||
| Duration of illness (years) | 9.9 ± 6.9 | – | – | – | ||
| Comorbidityb | – | – | – | |||
| None | 8 (47.1) | – | – | – | ||
| Depressive disorder | 9 (52.9) | – | – | – | ||
| Bipolar disorder | – | – | – | – | ||
| Personality disorder | – | – | – | – | ||
| OCD Baseline | OCD Follow-up | Statistical analysis | Tc | p | ||
|---|---|---|---|---|---|---|
| χ2 or Ta | p | |||||
| Y-BOCS scores | ||||||
| Total | 30.4 ± 4.1 | 21.2 ± 7.6 | – | – | 5.607 | < 0.001** |
| Obsession | 16.2 ± 2.1 | 11.3 ± 4.3 | – | – | 5.075 | < 0.001** |
| Compulsion | 14.2 ± 2.4 | 10.0 ± 3.6 | – | – | 5.716 | < 0.001** |
| HAM-D score | 11.5 ± 6.2 | 6.8 ± 5.6 | – | – | 5.015 | < 0.001** |
| HAM-A score | 12.4 ± 8.1 | 7.2 ± 6.2 | – | – | 4.703 | < 0.001** |
Data are shown as the mean ± standard deviation.
SD standard deviation, IQ intelligence quotient, Y-BOCS Yale-Brown Obsessive–Compulsive Scale, HAM-D Hamilton Rating Scale for Depression, HAM-A Hamilton Rating Scale for Anxiety.
**The mean difference is significant at the 0.005 level.
aIndependent t-test or Welch's t-test if the variances were not equal; χ2 analysis or Fisher's exact test for categorical data.
bNumber (percentage) of patients who were diagnosed with each comorbid psychiatric disorder.
cPaired-samples t-test.