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. 2020 Nov 13;8:595373. doi: 10.3389/fcell.2020.595373

FIGURE 8.

FIGURE 8

Diagram illustrating the beneficial effects of PC that improved reproductive ability in obese female mice by alleviating oxidative stress-induced ovarian and oocyte damage. The intragastric administration of PC reduced the number of atretic follicles and improved antioxidant enzymes in obese female mice ovaries. The administration of PC also rescued oocyte meiosis defects, including aberrant epigenetic effects, abnormal mitochondrial distribution, ROS accumulation, and early apoptosis. Therefore, ovary/oocyte quality, and the fertility of obese female mice was improved after PC administration.