TABLE 2.

Genotypic and phenotypic antibiotic resistance profiles of four CHDL-producing A. baumannii isolates.

Isolates	CHDL type	Chromosome/plasmid	Resistance genes	MIC (mg/L)
				PIPC	S/A	TAZ/PIPC	CAZ	CFPM	IPM	MEPM	DRPM	GM	TOB	AMK	MINO	CL	CPFX	LVFX	ST
Ab-B004d-c	OXA-23	Chromosome	blaADC-66, blaOXA-70, sul1, ant(3″)-IIa, aac(3)-IIa and blaCTX-M-15	>64	>8/16	>4/64	>16	>16	>8	>8	>8	>8	>8	8	0.5	≤2	>2	>4	>38/2
		Plasmid	dfrA1, mph(E), msr(E),tet(39), aac(3)-IId and blaOXA-23
Ab-D10a-a	OXA-23	Chromosome	blaADC-66,blaOXA-70, sul1, ant(3″)-IIa, aac(3)-IIa and blaCTX-M-15	>64	>8/16	>4/64	>16	>16	>8	>8	>8	>8	>8	16	0.5	≤2	>2	>4	>38/2
		Plasmid	dfrA1, mph(E), msr(E), tet(39), aac(3)-IId and blaOXA-23
Ab-C102	OXA-58	Chromosome	ant(3″)-IIa, blaOXA-699 and blaADC-32	64	1/2	4/32	8	4	1	1	0.5	0.5	2	2	≤0.25	≤2	0.5	≤1	>38/2
		Plasmid	aph(6)-Id, aph(3″)-Ib, sul2, aph(3′)-Ia, floR and blaOXA-58
Ab-C63	OXA-420	Chromosome	blaADC-87, blaOXA-51 and ant(3″)-IIa	>64	8/16	>4/64	4	8	4	4	4	>8	>8	2	0.5	4	>2	>4	>38/2
		Plasmid	mph(E), msr(E), tet(39), dfrA20, sul2, aph(6)-Id, aph(3″)-Ib, blaOXA-420, ant(2″)-Ia and aph(3’)-Ia

Abbreviations: PIPC, piperacillin; S/A, ampicillin-sulbactam; TAZ/PIPC, piperacillin-tazobactam; CAZ, ceftazidime; CFPM, cefepime; IPM, imipenem; MEPM, meropenem; DRPM, doripenem; GM, gentamycin; TOB, tobramycin; AMK, amikacin; MINO, minocycline; CL, colistin, CPFX, ciprofloxacin; LVFX, levofloxacin; ST, trimethoprim-sulfamethoxazole.