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. 2020 Nov 13;10:541262. doi: 10.3389/fonc.2020.541262

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Copyright © 2020 Li, Cao, Huang, Wu, Chen, Wang and Xiong

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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MTA1-knockdown down-regulates the EMT and EMT-associated HIF-α in MCF-7 cells. (1) Relationship between MTA1 and E-cadherin, N-cadherin, vimentin, ZO-1, snail1 and twist2, data from TCGA (A_1-6). (2) WB assay for EMT-associated protein in MCF-7 and MBA-MD-231 cell lines (B, C_1-6). (3) sh-MTA1 and NC-MTA1 cell lines of MCF-7 are treated with hypoxia for 0h, 6h and 12h, then detects the HIF-α level by WB (D_1-2). (4) Same treatment as in (3) which followed by IF assay (E).