Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Nov 13;11:598555. doi: 10.3389/fphar.2020.598555

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2020 Tsai, Xia and Sun

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

6-Gingerol regulates the expression of autophagy and ferroptosis related proteins in A549 cells. (A) The western blot analysis of USP14, Beclin 1, NCOA4, LC3 I, LC3 II, FTH1, TfR1, GPX4 and ATF4, Co-IP analysis of ubiquitination of K63 on Beclin one; (B) The densitometric analysis of the bands was presented as the relative ratio of USP14, Beclin 1, NCOA4, LC3 II/LC3 I, FTH1, TfR1, K63 ubiquitination on Beclin one to Beclin 1. (C) In vitro K63-linked deubiquitination of Beclin one by USP14. Con: control, 20-Gin: 20 μM 6-Gingerol, 40-Gin: 40 μM 6-Gingerol, 80-Gin: 80 μM 6-Gingerol. Compared with the control group, *p < 0.05, **p < 0.01. Data are expressed as mean ± SD (n = 3).