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. 2020 Nov 13;11:598555. doi: 10.3389/fphar.2020.598555

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Copyright © 2020 Tsai, Xia and Sun

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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6-Gingerol up-regulates the expression of LC3 and FTH1 in USP14-OE cells. (A) The western blot analysis of USP14 overexpression; (B) The cell viability of USP14-OE cells treated with 6-Gingerol; (C) The representative images of GFP-LC3 and DAPI; (D) The quantitative positive rate of GFP-LC3; (E) The western blot analysis of FTH1 in USP14-OE cells; (F) The western blot analysis of LC3 in USP14-OE cells; (G) The Co-IP analysis of ubiquitination of K63 on Beclin one in USP14-OE cells. Data are expressed as mean ± SD, *p < 0.05, **p < 0.01 (n = 3).