TABLE 1.

LncRNAs involved in BMSC regulation.

LncRNA	Relative expression	Role	Target	References
HOTAIR	Upregulation	Inhibits adipogenic differentiation of MSCs	DNA methylation	Kalwa et al., 2016
SEMA 3B-AS1	Upregulation	Inhibits proliferation and osteogenic differentiation of hMSCs	Proteins in actin cytoskeleton, FA	Zhang et al., 2019a
XIST	Upregulation	Inhibits osteoblast differentiation	Runx2, ALP	Chen et al., 2019c
AK016739	Downregulation	Promotes bone formation in osteoporosis mice	–	Yin et al., 2019
BDNF-AS	Upregulation	Inhibits osteogenic differentiation of BMMSCs	BDNF	Feng et al., 2018b
Bmncr	Upregulation	Stimulates bone formation in vivo	fibromodulin	Li et al., 2018a
Bmcob	Upregulation	Promotes osteoblastic differentiation of BMSC	SBP2	Sun et al., 2018
NEF	Upregulation	Promotes osteoporosis	IL-6	Ma et al., 2019

“–” Unknown.