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. 2020 Oct 20:1–10. doi: 10.1017/ice.2020.1273

Box 1.

Brief Summary of Available Literature on SARS-CoV-2 Shedding

Duration of Viral Shedding in Respiratory Samples Duration of Viral Shedding in Stool/Rectal Samples
  • The pooled median duration of viral RNA shedding in all severities of illness from respiratory isolates is 18.4 d (95% CI, 15.5–21.3). Intermittent RNA shedding up to 92 d after symptom onset has been observed.

  • Viable virus has been isolated via culture from −6 to 20 d relative to symptom onset.

  • Duration of RNA shedding exceeds the duration of viable virus shedding from 13 to 45 d.

  • Viral RNA shedding in stool has not been consistently observed. The pooled median duration of viral RNA shedding is 22.1 d (95% CI, 14.4–29.8). Viral RNA shedding up to 55 d after diagnosis has been observed.

  • Viable virus has been isolated via culture of stool on day 19 of illness.

  • Detection of stool RNA may lag behind detection of respiratory RNA by PCR.