Table 4C.
Adjusted logistic regression models: Baseline characteristics as predictors of T3 gait and balance outcomes (based on available literature).
| More tandem gait missteps (T3) | More near falls per year (T3) | Lower total ABC-6 score (T3) | ||
|---|---|---|---|---|
| OR (95% CI) | ||||
| Total tremor score | Adjusted model 1 | 1.07 (0.96–1.20)c | 1.04 (0.95–1.14)c | 1.09 (1.00–1.18)c |
| Adjusted model 2 | 1.08 (0.97–1.20)a | 1.08 (1.00–1.18)a | ||
| Tremor duration | Adjusted model 1 | 0.97 (0.94–0.99)c | 1.01 (0.99–1.03)b | 1.00 (0.98–1.02)f |
| Adjusted model 2 | ||||
| Cranial tremor score | Adjusted model 1 | 0.82 (0.50–1.34)c | 0.84 (0.55–1.26)e | 1.21 (0.83–1.75)e |
| Adjusted model 2 | 0.79 (0.48–1.29)a | 1.18 (0.84–1.66)a | ||
| Intention tremor | Adjusted model 1 | 0.05 (0.01–0.22)c | 1.49 (0.65–3.40)b | 0.86 (0.39–1.89)f |
| Adjusted model 2 | ||||
| MoCA | Adjusted model 1 | 0.77 (0.62–0.95)c | 0.79 (0.68–0.92)c | 0.77 (0.66–0.91)f |
| Adjusted model 2 | 0.76 (0.62–0.94)a | 0.76 (0.65–0.89)a | ||
| CDR | Adjusted model 1 | 1.31 (0.14–12.47)c | 5.77 (1.34–24.80)c | 2.29 (0.48–10.84)f |
| Adjusted model 2 | 1.31 (0.14–12.47)c | 6.04 (1.48–24.64)b | 2.38 (0.53–10.75)c | |
| Executive function | Adjusted model 1 | 0.41 (0.14–1.19)f | 0.40 (0.19–0.92)f | 0.35 (0.16–0.76)f |
| Adjusted model 2 | 0.38 (0.13–1.08)c | 0.39 (0.20–0.75)b | 0.35 (0.16–0.76)f | |
| Attention | Adjusted model 1 | 0.62 (0.32–1.21)c | 0.62 (0.35–1.10)b | 0.37 (0.21–0.67)f |
| Adjusted model 2 | 0.78 (0.45–1.37)b | 0.62 (0.35–1.10)b | 0.42 (0.25–0.72)b | |
| Visuo-spatial | Adjusted model 1 | 0.45 (0.20–1.02)c | 0.69 (0.37–1.27)b | 0.61 (0.32–1.15)f |
| Adjusted model 2 | ||||
| ESS | Adjusted model 1 | 1.02 (0.90–1.14)c | 1.03 (0.93–1.13)b | 1.08 (0.98–1.19)c |
| Adjusted model 2 | ||||
| IADLj | Adjusted model 1 | 0.65 (0.28–1.48)c | 0.83 (0.64–1.08)c | 0.71 (0.47–1.07)f |
| Adjusted model 2 | 0.61 (0.26–1.42)a | 0.65 (0.43–1.00)a | ||
| GDS-30 | Adjusted model 1 | 1.08 (0.97–1.20)c | 1.10 (1.02–1.19)b | 1.12 (1.03–1.21)c |
| Adjusted model 2 | ||||
| GAD-7j | Adjusted model 1 | 0.94 (0.81–1.09), p = 0.40c | 1.12 (0.99–1.27), p = 0.08b | 1.11 (0.98–1.25), p = 0.11c |
| Adjusted model 2 | ||||
| Average # of drinks per week | Adjusted model 1 | 1.02 (0.96–1.09)e | 0.98 (0.93–1.04)h | 1.02 (0.97–5.17)i |
| Adjusted model 2 | ||||
| Number of drinkers | Adjusted model 1 | 0.52 (0.19–1.43)c | 0.56 (0.24–1.28)b | 0.56 (0.26–1.20)f |
| Adjusted model 2 | ||||
ABC-6, Transformed Activities of Balance Confidence Scale score; CDR, Clinical Dementia Rating; CI, Confidence Interval; ESS, Epworth Sleepiness Scale; GAD-7, General Anxiety Disorder Seven-Item; GDS-30, Geriatric Depression Scale Thirty-Item; IADL, Instrumental Activities of Daily Living; MoCA, Montreal Cognitive Assessment; OR, Odds Ratio.
Adjusted model 1: Less restrictive model for confounding [an association (p < 0.05) between the confounding variable and either the independent or dependent variable] Adjusted model 2: More restrictive model for confounding an association (p < 0.05) between the confounding variable and both the independent and dependent variable. If cell is empty, this signifies that no variables met requirements for confounders and that results are the same as those in the unadjusted models.
All values represent odds ratio and 95% confidence interval. All measures of time were recorded in seconds.
Adjusted for age.
Adjusted for medications that can decrease gait and balance.
Adjusted for age and medications that can decrease gait and balance.
Adjusted for age and gender.
Adjusted for age, medications that can decrease gait and balance, and gender.
Adjusted for age, medications that can decrease gait and balance, and years of education.
Adjusted for age and gender.
Adjusted for medications that can decrease gait and balance and gender.
Adjusted for age, medications that can decrease gait and balance, education, and gender.
T2 is baseline assessment. Bolded values are significant in the hypothesized direction (p < 0.017).