Table 1.
Body weight and plasma parameters of control, L.G6pc−/−, L.Chrebp−/− and L.G6pc−/−.Chrebp−/− mice.
control mice (n = 8) | L.G6pc−/− mice (n = 6) | L.Chrebp−/− mice (n = 7) | L. G6pc−/−. Chrebp−/− mice (n = 8) | |
---|---|---|---|---|
Body weight (g) | 27.8 ± 1.3 | 26.7 ± 0.8 | 23.9 ± 1.1 | 20.7 ± 0.5∗∗∗,$ |
TG (g/L) | 1.41 ± 0.06 | 1.26 ± 0.09 | 1.56 ± 0.22 | 1.96 ± 0 .16∗,$$ |
Cholesterol (g/L) | 1.19 ± 0.08 | 1.23 ± 0.14 | 1.11 ± 0.08 | 3.32 ± 0.13∗,$$ |
NEFA (mg/dL) | 28.07 ± 2.84 | 25.64 ± 1.98 | 20.95 ± 1.56 | 23.08 ± 1.34 |
Glucose (mg/dL) | 162.3 ± 7.1 | 141.7 ± 13.0 | 179.6 ± 5.6 | 103.5 ± 7.5∗∗∗,$ |
The results are expressed as mean ± s.e.m. A one-way ANOVA followed by Tukey's post hoc test was performed as a statistical analysis. ∗p < 0.05, ∗∗p < 0.01 and ∗∗∗p < 0.001 versus WT mice. $p < 0.05 and $$p < 0.01 versus L.G6pc−/− mice; n = number of samples.