Table 2.

The role of OCT4-related complexes in cancer stem cells

Complex	The role in cancer stem cells (CSCs)
OCT4/SOX2 complex	Gene transcription, cell localization, DNA repair, cell cycle, apoptosis
Oct4/Sox2/Zfp206 complex	Maintains stemness of CSCs
OCT4/SOX2/NANOG complex	Inhibition of differentiation
Oct4/KLF4/β-catenin complex	Maintains stemness of CSCs
OCT4/SALL4 complex	Maintains stemness of CSCs
OCT4/Cav-1 complex	Degradation of OCT4
OCT4/PKM2 complex	Gene transcription
Ash2I/OSN complex	Gene transcription
ABCG2/OCT4 complex	Maintains stemness of CSCs
Oct4/Sox2/KLF4 complex	The expression of Nanog