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. 2020 Jul 23;8(4):699–708. doi: 10.1016/j.esxm.2020.06.009

Table 2.

Linear regression models of female sexual function index scores and demographics, health status, and marijuana use habits

Characteristic Total FSFI
 Desire domain
 Arousal domain
 Lubrication domain
 Orgasm domain
 Satisfaction domain
 Pain domain
β P value β P value β P value β P value β P value β P value β P value
Age, y
 <30 Ref Ref Ref Ref Ref Ref Ref
 30–39 −1.32 .12 −0.29 .11 −0.28 .14 −0.08 .69 −0.25 .24 −0.40 .06 −0.02 .91
 40–49 −0.32 .71 −0.30 .10 −0.15 .42 −0.09 .62 0.11 .62 −0.08 .73 0.19 .31
 50–59 −2.08 .03∗ −0.54 .008∗ −0.53 .01∗ −0.57 .008∗ −0.14 .57 −0.16 .51 −0.14 .50
 60+ −1.32 .21 −0.48 .03∗ −0.22 .34 −0.48 .04 0.29 .27 −0.22 .40 −0.21 .38
Race
 White Ref Ref Ref Ref Ref Ref Ref
 Black −1.06 .46 0.02 .94 −0.26 .40 −0.03 .93 −0.58 .10 −0.40 .27 0.18 .56
 Hispanic 0.69 .42 0.45 .01∗ 0.22 .25 0.19 .30 −0.09 .68 −0.11 .62 0.02 .90
 Other −2.12 .02∗ −0.21 .27 −0.51 .01∗ −0.33 .10 −0.70 .002∗ −0.22 .33 −0.16 .42
Relationship status
 Married/in a relationship Ref Ref Ref Ref Ref Ref Ref
 Single 0.86 .21 0.23 .12 0.43 .005∗ 0.24 .12 0.06 .71 −0.19 .28 0.09 .57
Region
 West Ref Ref Ref Ref Ref Ref Ref
 International −0.18 .82 0.00 .99 −0.08 .63 0.10 .54 −0.05 .80 −0.11 .57 −0.04 .80
 Midwest 1.87 .07 0.16 .46 0.37 .09 0.41 .07 0.48 .06 0.51 .05∗ −0.06 .78
 Northeast −0.33 .66 −0.05 .77 −0.10 .53 −0.02 .89 −0.04 .82 −0.19 .31 0.07 .66
 South 0.79 .30 0.03 .87 −0.03 .85 0.36 .03∗ 0.00 .99 0.11 .56 0.32 .05∗
BMI
 Normal Ref Ref Ref Ref Ref Ref Ref
 Underweight −2.91 .11 −0.01 .97 −0.53 .19 −1.14 .01 −0.63 .17 −0.33 .48 −0.28 .49
 Overweight 0.34 .59 0.03 .82 0.08 .59 0.08 .55 0.02 .91 −0.05 .73 0.19 .18
 Obese 0.16 .85 0.02 .91 0.06 .75 0.12 .52 0.10 .63 −0.21 .33 0.06 .73
 Extremely obese 0.43 .65 −0.08 .68 0.06 .76 0.01 .95 0.39 .11 −0.04 .88 0.09 .67
Tobacco use
 Never Ref Ref Ref Ref Ref Ref Ref
 Current 0.92 .27 0.14 .42 0.17 .36 0.17 .37 0.25 .25 0.06 .79 0.14 .45
 Former −0.01 .98 0.12 .31 −0.04 .76 0.09 .46 −0.08 .59 −0.15 .29 0.04 .77
PCP visits in last 3 mo
 0.00 Ref Ref Ref Ref Ref Ref Ref
 1.00 −0.91 .12 −0.23 .07 −0.14 .28 −0.12 .38 −0.11 .47 −0.24 .11 −0.02 .88
 2+ −0.62 .43 −0.06 .71 −0.10 .58 −0.17 .32 −0.06 .78 −0.03 .87 −0.10 .57
Cannabis use frequency (continuous) 0.61 .0004∗ 0.09 .02∗ 0.14 .0002∗ 0.07 .08 0.14 .002∗ 0.13 .003∗ 0.05 .20
Method of consumption
 Smoking flower Ref Ref Ref Ref Ref Ref Ref
 Edibles −0.59 .51 −0.11 .55 −0.11 .59 −0.19 .34 −0.08 .73 −0.01 .98 −0.10 .60
 Other −1.22 .36 −0.03 .90 −0.10 .72 0.11 .71 −0.15 .66 −0.36 .27 −0.68 .02∗
 Smoking concentrates −1.67 .16 −0.23 .36 −0.06 .82 −0.28 .29 −0.59 .05 −0.30 .32 −0.28 .41
 Tincture or oils −0.09 .91 −0.04 .82 0.19 .30 −0.12 .53 0.09 .67 −0.25 .23 0.04 .85
 Vaping 0.04 .96 −0.13 .44 −0.06 .70 0.19 .27 −0.03 .89 −0.11 .58 0.18 .30
Primary reason for use
 Medical Ref Ref Ref Ref Ref Ref Ref
 Recreational 1.03 .15 0.22 .14 0.21 .18 0.01 .93 0.27 .13 0.29 .11 0.03 .83
Cannabinoid
 THC dominant Ref Ref Ref Ref Ref Ref Ref
 Both THC and CBD 0.32 .57 0.06 .61 0.11 .39 0.15 .24 0.21 .14 0.06 .69 −0.26 .03∗
 CBD dominant 0.28 .77 0.09 .66 −0.07 .74 0.15 .50 0.21 .40 0.01 .96 −0.10 .64
Total comorbidities (continuous) −0.44 .04∗ −0.03 .44 −0.05 .33 −0.08 .08 −0.11 .04∗ −0.09 .09 −0.08 .07

BMI = body mass index; CBD = cannabidiol; FSFI = female sexual function index; OR = odds ratio; PCP = primary care physician; THC = tetrahydrocannabinol.

Comorbidities included hypertension, diabetes, heart disease, arthritis, lung disease, kidney disease, thyroid disease, hypercholesterolemia, cancer, neurologic disease, liver disease, depression, and anxiety.

Region represents primary residence.

∗

Significant (P < .05)