Table 3.
Case series: clinicopathological information and outcomes.
| Patients | Age | Primary tumor | Clinical stage | G | Neoadj therapy | Surgery | R | Nodal status | Adj Therapy | DFS/PFS | OS | Follow up |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Case 1 | 78 | Parotid | III | 3 | Yes | Total Parotidectomy + SND | 0 | 0 | RT | 20 | 20 | NEDa |
| Case 2 | 35 | Parotid | IVA | 3 | Yes | Radical Parotidectomy+ RMND | 0 | + | RTCT | 4 | 5 | DODb |
| Case 3 | 30 | Parotid | IVA | 3 | No | Radical Parotidectomy + RMND | 0 | + | RT | 10 | 11 | DOD |
| Case 4 | 87 | Parotid | IVA | 3 | No | Radical Parotidectomy + RMND | 0 | + | RT | − | − | LF |
| Case 5 | 80 | Parotid | II | 2 | No | Radical Parotidectomy + RMND | 0 | 0 | No* | 30 | 31 | DOD |
| Case 6 | 55 | Parotid | IVa | 3 | No | Radical Parotidectomy + RMND | 0 | + | RTCT | 120 | 120 | NED |
| Case 7 | 85 | Parotid | IVa | 3 | No | Radical Parotidectomy + RMND | 0 | + | RT | 24 | 24 | NED |
| Case 8 | 43 | Parotid | IVb | 1 | No | Radical parotidectomy + RMND | 0 | 0 | No | 5 | 6 | DOD |
| Case 9 | 57 | Parotid | IVa | 3 | No | Radical Parotidectomy + RMND | 0 | + | RT | 4 | 4 | LF |
| Case 10 | 75 | Submandibular | IVc | 3 | No | / | / | / | No | 2 | 4 | DOD |
| Case 11 | 80 | Submandibular | IVa | 3 | No | Sialoadenectomy + RMND | 0 | 0 | RT | 21 | 21 | NED |
| Case 12 | 65 | Submandibular | IVa | 3 | Yes | Sialoadenectomy + RMND | 0 | 0 | No* | 13 | 13 | NED |
NED: no evidence of disease; DOD: death of disease; LF: lost in follow up; R: residual disease; DFS: disease free survival; OS: overall survival; Adj: adjuvant; SND: simplified neck dissection; RMND: modified radical neck dissection; RT: radiotherapy; RTCT: radiochemotherapy.
*
Patient refused adjuvant treatment.