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. 2020 Nov 25;10(4):2045894020972273. doi: 10.1177/2045894020972273

Table 2.

Sub-maximum CPET parameters.

Control (n = 18) Ipc-PH (n = 19) Cpc-PH (n = 27)
Time between RHC and sub-maximum CPET, median (IQR), days 51 (10–107) 19 (8–34) 15 (8–23)
ETCO2 (mmHg) 35 ± 5 38 ± 4 34 ± 4b
Rest SpO2 (%) 97 ± 1 95 ± 2a 95 ± 2a
Peak SpO2 (%) 95 ± 2 90 ± 3a 90 ± 4a
RER 1.03 ± 0.1 1.03 ± 0.1 1.04 ± 0.1
VE/VCO2 31 ± 10 31 ± 7 41 ± 11a,b
Delta ETCO2 (mmHg) 1.9 ± 5.0 −0.2 ± 4.0 −3.6 ± 3.4a,b
GXCAP (mL*mmHg) 611 ± 247 541 ± 141 348 ± 137a,b
OUES (% predicted) 102 ± 22 79 ± 20a 61 ± 15a,b
O2 pulse (mL/O2/beat) 180 ± 102 101 ± 22a 98 ± 36a
Sub-maximum VO2 (% predicted) 98 ± 18 64 ± 11a 60 ± 18a
Extrapolated maximum VO2(% predicted) 121 ± 44 69 ± 18a 62 ± 21a

Note: Data presented as no. (%) or mean ± SD unless otherwise stated.

CPET: cardiopulmonary; Ipc-PH: isolated post-capillary pulmonary hypertension; Cpc-PH: combined pre-and post-capillary pulmonary hypertension; RHC: right heart catheterization; ETCO2: end tidal carbon dioxide; SpO2: peripheral oxygen saturation; RER: respiratory exchange ratio; VE/VCO2: ventilatory efficiency; GXCAP: gas exchange derived pulmonary vascular capacitance; OUES: oxygen uptake efficiency slope; VO2: oxygen consumption.

ap-value < 0.05 vs. controls.

bp-value < 0.05 vs. Ipc-PH.